For Authors

Genetics in the 3 rd Millennium (G3M) is an independent peer-reviewed open access scientific journal that

publishes articles, with the following specifications, in all fields of genetics.


To provide informative and up-to-date articles in the fields of genetics, especially medical/ human genetics, for physicians, related medical groups, interested students and Iranians all over the world.

To present research, genetic services and advances in this field, in our country.

To introduce and make possible communication between Iranian researchers from all over the world.

Article Submission

G3M welcomes submission of articles in English. These submissions should not have been previously published elsewhere and should not be submitted anywhere pending the decision of G3M. 

Research articles should include an Abstract (at most 300 words), Keywords (3-8 words based on MESH system), Introduction, Material and Methods, Results, Discussion, Acknowledgement (if necessary), References, Table legends, and Figure legends.

Solicited review articles published in G3M are intended to provide accessible insightful information on timely topics in the field of genetics.

Review articles are to be between 7 and 12 printed pages (approximately 900 words per page) and should include the following sections: Introduction, body, Conclusions, Acknowledgments, Web Resources (as necessary), and References.

The body of the text may be divided with bold headings and further subdivided with italic headings. The Conclusions section should contain speculation regarding the future of the reviewed topic. Figures and tables may be included. Please note that proper copyright permissions are required for display items previously published in any form.. For review articles, according to the standards of the journal, at least one of the authors must be an assistant professor (or higher) and the authors must have published at least two research articles relevant to the topic of the review article and cite them in the manuscript.

Case reports of rare cases will be considered for publication (in limited numbers). They should include clinical and paraclinical findings and up-to-date information in the following format: Introduction, Case Presentation, and Discussion. The length of the text should not exceed 6 pages double spaced, or should be limited to 500 words, including abstract with at most 3 tables or figures and captions. Literature reviews, short communication and letters to editor are also welcome in specific formats not exceeding 1-2 pages.

Correspondence and Manuscript Submission

Manuscripts must be submitted online in a double-spaced format, with pages numbered, in at least 12-point type, do not insert line numbers. Any manuscript without page numbers will not be considered and will be returned immediately to the author. Please note that lack of proper formatting, spelling, and reference citations will slow down a paper’s review and its ultimate disposition, so these items should be checked before submission. Once the manuscript has been prepared according to the information below, please visit to submit it. Each manuscript, when submitted, must include a word count for both the abstract and the text, exclusive of references, tables, and figure legends. If the manuscript cannot be submitted online, you may also email your manuscript to The author who submits the manuscript will remain the contact author throughout the entire publishing process. When the final revision of the manuscript has been accepted, the senior author must sign a Publication Agreement (see "Copyright").

Ethical policy

Please note that the cover letter must include a statement declaring the regulatory compliance of the research work with the current ethical protocol concerning the clinical trial study for both human and animal subjects.

In addressing ethical considerations, the authors reporting the results of experimental investigations on human subjects must include the statement of assurance in the Materials and Methods section of the manuscript that: (i) An informed consent has been obtained that indicates the purposes of the research procedure, the expected duration of the subject's participation, and identification of any procedures that are experimental in compliance with the ethical guidelines of the Declaration of Helsinki notified in: as a priori approval by an institutional human research committee and (ii) The experimentations on animal subjects have been in accordance with the criteria outlined in the “Guide for the Care and Use of Laboratory Animals” given in:

Conflict of Interest

As an integral part of the submission process, corresponding authors are required to confirm whether they or their coauthors have any conflicts of interest to declare, and to provide details of these. If the corresponding author is unable to confirm this information on behalf of all coauthors, the authors in question will then be required to submit a completed Conflict of Interest Form to the Editorial Office. It is the corresponding author’s responsibility to ensure that all authors adhere to this policy.

If the manuscript is published, Conflict of Interest information will be communicated in a statement in the published paper.


The Genetics in the Third Millennium considers manuscripts for which copyright has not been assigned, that do not essentially duplicate already published material, and are not being simultaneously considered for publication elsewhere. If the submitted manuscript is based on the findings of an article in press or if such an article is cited in support of current findings, a copy of the article should be uploaded along with the submitted manuscript. Click here to download a copy of Disclaimer.

Cases of suspected plagiarism are taken very seriously by the journal and are subject to a set of formal procedures and penalties. Upon detecting plagiarism, the plagiarized manuscript will be rejected and new manuscripts will not be accepted from the person(s) at fault. Moreover, necessary correspondence will be made with the Deputy of Research with where authors are affiliated.

Reports of original research are published in the form of Original Contributions or Brief Original Contributions, comprising field and laboratory studies of infectious diseases and noninfectious acute and chronic diseases, as well as studies of statistical or methodological issues.

Letters to the Editor should refer to an article(s) previously published in the Journal . A letter should convey the author's views as concisely as possible and contain a reasonable number of references. We do not allow publication of original research results in Letters to the Editors. Letters to the Editor are not blinded. After it is accepted, it is usually sent to the first author of the original paper for a response; if a response is warranted, both letters will appear in the same issue. (If the response letter cannot be submitted within 3-4 weeks, we will publish the letter and the response can be published in a future issue.) The responding author(s) should reference the critique before citing any other references. The response from the original author ends the discussion.


Revisions should be submitted online or through email using the same "Contact Author" account as the original manuscript. Authors are requested to upload an unblinded copy showing the changes, deletions, and/or additions. Along with these copies, responses to the editor's and reviewers' comments are also requested.


It is a condition of publication in the Genetics in the Third Millennium that authors grant an exclusive license to the Journal. This ensures that requests from third parties to reproduce articles are handled efficiently and consistently and will also allow the article to be as widely disseminated as possible. In granting an exclusive license, authors may not use their own material in other publications

Upon receipt of accepted manuscripts at Genetics in the Third Millennium , authors will be invited to complete an copyright licence to publish form.

Please note that by submitting an article for publication you confirm that you are the corresponding/submitting author and that Genetics in the Third Millennium may retain your email address for the purpose of communicating with you about the article. You agree to notify Genetics in the Third Millennium immediately if your details change. If your article is accepted for publication, Genetics in the Third Millennium will contact you using the email address you have used in the registration process. Please note that Genetics in the Third Millennium does not retain copies of rejected articles.

Word Count

An abstract should not exceed 300 words. As noted above, when a manuscript is submitted, authors must provide a word count for both the abstract and the text. Editors can request that authors shorten their papers further. Lengthy, encyclopedic tables should be avoided.

Text Format and Style

Refer to a current issue of the Journal for the correct format and style.

If you have additional questions about Journal style after reading the following instructions, please contact the Journal office, and an Editorial Project Manager will assist you.

Cover letter. Provide a cover letter including 1) the name and type of the manuscript; 2) the names of the authors with degrees and affiliations, and information on each author’s individual contributions; for example, “Author A designed the study and directed its implementation, Author B ….”; and 3) Grant information, for example "This work was supported by the National Institutes of Health (Grants P50 CA098252 and CA118790 to R. B. S. R.); and the Alcohol & Education Research Council (Grant HY GR667789)." 

Each affiliation should be as detailed as possible (e.g., section, unit, department; division; School at the University; University Name; City and State or Country). Write out names of states, provinces, and countries. Use asterisk (*) next to the corresponding author’s name.

Click here to download a sample of the cover letter.

Important note: Please only include the authors' names and affiliations in the cover letter and DO NOT repeat them in the manuscript. 

Important note: Authorship credit should be based on criteria developed by the International Committee for Medical Journal Editors (ICMJE): (1) substantial contributions to conception and design, or acquisition of data, or analysis and interpretation of data; (2) drafting the article or reviewing it and, if appropriate, revising it critically for important intellectual content; (3) final approval of the version to be published. Authors should meet conditions (1) and (2) and (3).

Title page. The title page should only include the title and running title, a short title of not more than 50 letters and spaces.

Footnote. Use footnotes to describe all abbreviations used in the manuscript and their definitions. Footnotes must be numbered continuously starting with 1.

Acknowledgments section. This section should be placed after the text and before the references. Provide an ordered list of material that may be included: 1) thank-you’s (in this part only, "Dr." should precede the name of each person with a medical and/or doctoral degree (e.g., “The authors thank Dr. John Smith for his contributions to this study.”); 2) conflict of interest statement.

Abstract. Except for letters to the editor and book reviews, all submissions, including stand-alone commentaries, must include an abstract. The abstract should state concisely the research question that was asked, the methods used, the results of the research, and the answer to the research question. Because the abstract is used by abstracting services such as MEDLINE and must make sense when read alone, it should not include citations of the scientific literature or figures or tables. However, it should include the study year(s), location, and population studied, if applicable.

Note: The abstract must be limited to 300 words . The Journal does not use structured abstracts. Type the abstract as one double-spaced paragraph.

Keywords. For all submissions, including commentaries, give a list of 3-8 keywords below the abstract. Make sure the key words are MeSH terms.

Text headings.

The main headings used in Original Contributions are INTRODUCTION, MATERIALS AND METHODS, RESULTS, DISCUSSION, ACKNOWLEDGEMENTS, and REFERENCES. (These headings may not apply to statistical papers.) Place them flush left on the page in capital bold letters; do not underline.

Second-level headings are flush left with only the first letter of the first word uppercased. Use bold letters. Do not underline.

Third-level headings are italic and begin the paragraph (with only the first letter of the first word uppercased), followed by a period. Use bold letters. 

Do not number the sections of the paper.

Abbreviations. To improve clarity and readability, the Journal strictly limits the use of abbreviations. Only those needed for long, involved terms, such as hepatitis B surface antigen (HBsAg), will be allowed. To be considered, abbreviations must be used at least 3 times after the initial callout in the text. Do not use abbreviations in the abstract. The abbreviations CI, RR, OR, and SMR may be used only in parentheses after being defined the first time used. Abbreviations may be used in tables and figures if they are defined in the table footnotes and figure legends. Avoid excessive use of abbreviations solely to limit the word count. 

Use of "percent" in text. Use the % symbol in the abstract, text, tables, and figures (including legends). Use mg/100 mL rather than mg%.

Numbers. Use Arabic numerals for all specific numbers. Insert commas in numbers with 4 or more digits.

Metric system. The Journal strongly encourages authors to use the metric system for all measurements. Where US measurements must be used, metric equivalents must be given in parentheses.

Decimal fractions. For decimal fractions less than 1.00, use a zero in the whole-number position (e.g., 0.001).

Means, standard deviations, and standard errors. To report means, standard deviations, and standard errors, use the following format: "mean (SD)" and "mean (SE)." Do not use "±."

Table Format and Style

Each table must be formatted by using the table feature in Word. Tables should be numbered (Arabic numerals) in the same consecutive sequence in which they are mentioned in the text in a separate file. Do not include tables in the manuscript. They should be concise and self-explanatory., Mark the location of each table in the text as "Table 1 Here".

Order of footnotes: 1) Abbreviations: (no footnote symbol, listed alphabetically, separated by semicolons); 2) P values; 3) other footnotes as necessary, each preceded by a superscript lowercase letter.

Always list any P values after the abbreviations and before other footnotes in the table.

Requirements for Figures

Letters, numbers, decimal points, and symbols should be large enough and sharp enough to be readable when figures are reduced and scanned (no smaller than 8 pt in print). All figures will be reduced to fit either in 1 column or within the 2 column width of the Journal page. On maps, add scale (in kilometers or meters) and direction north.

Figure legends should not be included on the figures themselves but should be typed after the reference list. Each legend should be a separate paragraph and should include details on the place of the study, the time of the study, and the study population (if applicable). Define all figure abbreviations in the legend.

Submit your figures in a separate file with TIFF format with resolution not less than 300 dpi.

Mark the location of each figure in the text as "Figure 1 Here"

Please note that it is the responsibility of the author(s) to obtain permission from the copyright holder to reproduce figures or tables that have previously been published elsewhere.


Number references consecutively in the order in which they are mentioned in the text. Reference numbers in the text are full-sized Arabic numerals in parentheses within the sentence. For 3 or more consecutive references cited all at once, use, for example, (1-4). Format other references as (4,5,12), with no spaces between the reference numbers.

Important: All statements of scientific fact should be referenced . Failure to do so may cause considerable delay in processing the manuscript and may necessitate renumbering of the references.

References to personal, written communications should be inserted in parentheses in the text rather than in the reference list. Give the person's name, institutional affiliation, "personal communication," and the year. Verbal communications are not acceptable as supporting documentation.

The reference list should be limited to published or "in press" references. No "submitted" manuscript should appear in the reference list. A manuscript submitted for publication but not yet accepted may be referenced in parentheses in the text. Give the author's name, institutional affiliation, and "unpublished manuscript." Unpublished data may also be cited in the text (e.g., communications with the paper’s coauthors). However, authors should not refer to "forthcoming" papers or promise future publication of results.

References must be verified by the author(s) against the original documents and must give the exact authors' last names, initials, and article title. Please supply the entire page range and issue number (in parentheses); see examples below. If only 1 page number is given, indicate in parentheses after the title whether the reference is a letter, an editorial, or an abstract. Articles that are accepted but not published, articles published online ahead of print, congress abstracts, and dissetations cannot be cited.

For articles originally published in a language other than English, indicate the language in parentheses after the article title provided in English.

Examples of correct forms of references follow. Type references double-spaced. The titles of journals should be abbreviated according to the List of Journals Indexed in Index Medicus (published by the National Library of Medicine). For more than 6 authors, list the first 3 and add "et al." 

It is strongly recommended that authors use a reference management software like Endnote. Click here to download citation style for Endnote.

Examples of Reference Style

Standard journal article

Nakajima S, Saijo Y, Kato S, et al. Effects of prenatal exposure to polychlorinated biphenyls and dioxins on mental and motor development in Japanese children at 6 months of age. Environ Health Perspect 2006;114(5):773–778.

Article in an online-only journal that accounts for the lack of a page range

Laupland KB, Davies HD, Low DE, et al. Invasive group A streptococcal disease in children and association with varicella-roster virus infection. Ontario Group A Streptococcal Study Group. Pediatrics. 2000;105(5):E60.


Rothman KJ, Greenland S, eds. Modern Epidemiology. 2nd ed. Philadelphia, PA: Lippincott-Raven, Publishers; 1998.

Chapter in a Book

Robins JM. Marginal structural models versus structural nested models as tools for causal inference. In: Halloran ME, Berry D, eds. Statistical Models in Epidemiology, the Environment, and Clinical Trials. New York, NY: Springer-Verlag; 1999:95–134.

Chapter in a book (no chapter titles)

Robins JM. Chapter 3. In: Halloran ME, Berry D, eds. Statistical Models in Epidemiology, the Environment, and Clinical Trials. New York, NY: Springer-Verlag; 1999:95–134.

Web page/Web site

Bureau of the Census, US Department of Commerce. Glossary of basic geographic and related terms—Census 2000. Washington, DC: Bureau of the Census; 2001. ( (Accessed February 24, 2005).

US Environmental Protection Agency. Final rule. "National primary drinking water regulations; arsenic and clarifications to compliance and new source contaminants monitoring." Part VIII. Federal Register 66, no. 14 (January 22, 2001):6876–7066. (

 Health Care Financing Administration. 1996 statistics at a glance. Baltimore, MD: Health Care Financing Administration; 1996. ( (Accessed March 1, 1998).


All proofs are transmitted by e-mail as an attachment. When they are received, they should be read carefully, corrected if necessary, and returned within 2 working days of receipt.

Language Editing

Before submitting your manuscript you may want to have it edited for correct usage of American English, particularly if English is not your first language. This step is not mandatory, but may help to ensure that the academic content of your paper is fully understood by journal editors and reviewers. Language editing does not guarantee that your manuscript will be accepted for publication. There are specialist language editing companies that offer quality services, and you can use any of these. Authors are liable for all costs associated with such services.


All authors of manuscripts accepted for publication must sign an agreement, transferring copyright to the Genetics in the Third Millennium Journal. Click here to download a copy of the Copyright Transfer form. Materials published in the journal may not be reproduced or published elsewhere without written consent of publisher:

All received articles that meet the journal's qualifications, will be sent for assessment by specialists- chosen at the discretion of the journal, without name or any information of author(s). Their comments and reviews will be submitted to the corresponding author for corrections. The authors are responsible for the contents of the articles. Articles will be edited to conform to journal style by the editorial board. The articles will be edited and returned to the author for confirmation before publication. The author(s) are responsible for the return of corrected pages to the publisher by the designated deadline. Delayed articles may not be published. The published material does not necessarily reflect the views of the journal. Ten copies will be sent to author(s) free of charge. Additional copies must be ordered.