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:: دوره 14، شماره 4 - ( 9-1395 ) ::
جلد 14 شماره 4 صفحات 4400-4407 برگشت به فهرست نسخه ها
The Role of HOXA Cluster Genes in Human Body Plan
چکیده:   (2048 مشاهده)

Homeobox (HOX) genes are contributed in the genetic control of development of the body plan, pattern formation, and cell fate determination and the other several key developmental processes. HOX genes are also known as selector genes because expression within a given section of the embryo will cause its cells to choose a particular developmental path. HOX genes encode transcription factors that conduct embryological development as well as regulate differential endometrial gene expression with each menstrual cycle. HOX genes have been arranged in four clusters of A, B, C and D that each has parallel and overlapping expression domains. Among these clusters, HOXA cluster that is the main focus of this paper has an important role in regulating various processes in human body. In the present paper, the expression of HOXA9, HOXA10, HOXA11, and HOXA13 genes in the developmental processes related to the reproductive tract and the expression of HOXA1, HOXA2, HOXA3, HOXA4, HOXA5, HOXA6 and HOXA7 genes in the other sections of human body are highlighted. 

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موضوع مقاله: تخصصي
دریافت: ۱۳۹۵/۹/۲۴ | پذیرش: ۱۳۹۵/۹/۲۴ | انتشار: ۱۳۹۵/۹/۲۴
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Kalantar S M, Mokhtari V. The Role of HOXA Cluster Genes in Human Body Plan. G3M. 2016; 14 (4) :4400-4407
URL: http://g3m.ir/article-1-1147-fa.html
The Role of HOXA Cluster Genes in Human Body Plan. ژنتیک در هزاره سوم. 1395; 14 (4) :4400-4407

URL: http://g3m.ir/article-1-1147-fa.html

دوره 14، شماره 4 - ( 9-1395 ) برگشت به فهرست نسخه ها
ژنتیک در هزاره سوم Genetics in the 3rd millennium
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